{"id":7368,"date":"2025-04-01T00:09:44","date_gmt":"2025-03-31T16:09:44","guid":{"rendered":"https:\/\/www.360mdi.com\/archives\/7368"},"modified":"2025-04-01T00:09:44","modified_gmt":"2025-03-31T16:09:44","slug":"1-%e7%94%b2%e5%9f%ba%e5%92%aa%e5%94%91%ef%bc%88lupragen-nmi%ef%bc%89%e7%9a%84%e6%9b%bf%e4%bb%a3%e5%93%81%e7%a0%94%e7%a9%b6%ef%bc%9a%e5%af%bb%e6%89%be%e6%9b%b4%e7%8e%af%e4%bf%9d%e7%9a%84%e8%a7%a3","status":"publish","type":"post","link":"https:\/\/www.360mdi.com\/archives\/7368","title":{"rendered":"1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u7684\u66ff\u4ee3\u54c1\u7814\u7a76\uff1a\u5bfb\u627e\u66f4\u73af\u4fdd\u7684\u89e3\u51b3\u65b9\u6848"},"content":{"rendered":"
\u5728\u5316\u5b66\u5de5\u4e1a\u7684\u4e16\u754c\u91cc\uff0c1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u5316\u5408\u7269\uff0c\u5e7f\u6cdb\u5e94\u7528\u4e8e\u73af\u6c27\u6811\u8102\u56fa\u5316\u5242\u3001\u50ac\u5316\u5242\u548c\u8868\u9762\u6d3b\u6027\u5242\u7b49\u9886\u57df\u3002\u7136\u800c\uff0c\u968f\u7740\u5168\u7403\u5bf9\u73af\u5883\u4fdd\u62a4\u610f\u8bc6\u7684\u4e0d\u65ad\u63d0\u9ad8\uff0c\u8fd9\u79cd\u5316\u5408\u7269\u7684\u4e00\u4e9b\u6f5c\u5728\u95ee\u9898\u4e5f\u9010\u6e10\u6d6e\u51fa\u6c34\u9762\u3002\u4f8b\u5982\uff0c\u5176\u751f\u4ea7\u8fc7\u7a0b\u4e2d\u53ef\u80fd\u4ea7\u751f\u7684\u6c61\u67d3\u4ee5\u53ca\u5bf9\u73af\u5883\u548c\u5065\u5eb7\u7684\u957f\u671f\u5f71\u54cd\uff0c\u4f7f\u5f97\u79d1\u5b66\u5bb6\u4eec\u5f00\u59cb\u601d\u8003\uff1a\u662f\u5426\u53ef\u4ee5\u627e\u5230\u4e00\u79cd\u66f4\u52a0\u73af\u4fdd\u4e14\u9ad8\u6548\u7684\u66ff\u4ee3\u54c1\uff1f\u672c\u6587\u5c06\u5e26\u4f60\u6df1\u5165\u4e86\u89e31-\u7532\u57fa\u54aa\u5511\u7684\u7279\u6027\u53ca\u5176\u66ff\u4ee3\u54c1\u7684\u7814\u7a76\u8fdb\u5c55\uff0c\u5e76\u63a2\u8ba8\u5982\u4f55\u901a\u8fc7\u521b\u65b0\u6280\u672f\u5b9e\u73b0\u66f4\u53ef\u6301\u7eed\u7684\u672a\u6765\u3002<\/p>\n
\u5982\u679c\u4f60\u628a\u5316\u5b66\u5de5\u4e1a\u6bd4\u4f5c\u4e00\u4e2a\u5e9e\u5927\u7684\u53a8\u623f\uff0c\u90a3\u4e481-\u7532\u57fa\u54aa\u5511\u5c31\u662f\u4e00\u79cd\u4e0d\u53ef\u6216\u7f3a\u7684\u8c03\u5473\u6599\u3002\u5b83\u80fd\u8ba9\u67d0\u4e9b\u53cd\u5e94\u66f4\u5feb\u3001\u66f4\u9ad8\u6548\u5730\u8fdb\u884c\uff0c\u5c31\u50cf\u76d0\u80fd\u8ba9\u98df\u7269\u7684\u5473\u9053\u66f4\u52a0\u7a81\u51fa\u4e00\u6837\u3002\u4f46\u95ee\u9898\u662f\uff0c\u8fd9\u9053\u201c\u8c03\u6599\u201d\u53ef\u80fd\u5e76\u4e0d\u50cf\u6211\u4eec\u60f3\u8c61\u4e2d\u90a3\u4e48\u5065\u5eb7\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u9700\u8981\u5bfb\u627e\u4e00\u79cd\u65b0\u7684\u201c\u8c03\u6599\u201d\uff0c\u65e2\u80fd\u6ee1\u8db3\u70f9\u996a\u9700\u6c42\uff0c\u53c8\u4e0d\u4f1a\u5bf9\u73af\u5883\u9020\u6210\u8d1f\u62c5\u3002\u63a5\u4e0b\u6765\uff0c\u8ba9\u6211\u4eec\u4e00\u8d77\u8d70\u8fdb\u8fd9\u4e2a\u5145\u6ee1\u6311\u6218\u4e0e\u673a\u9047\u7684\u9886\u57df\u5427\uff01<\/p>\n
1-\u7532\u57fa\u54aa\u5511\uff08C5H7N2\uff09\u662f\u4e00\u79cd\u542b\u6709\u6c2e\u539f\u5b50\u7684\u6742\u73af\u5316\u5408\u7269\uff0c\u5176\u5206\u5b50\u5f0f\u4e3aC5H7N2\uff0c\u5206\u5b50\u91cf\u4e3a99.13 g\/mol\u3002\u5b83\u7684\u5316\u5b66\u7ed3\u6784\u5982\u4e0b\u6240\u793a\uff1a<\/p>\n
C\n \/ \n N C\n | |\n C C\n | |\n N H<\/code><\/pre>\n\u4ece\u7269\u7406\u6027\u8d28\u6765\u770b\uff0c1-\u7532\u57fa\u54aa\u5511\u662f\u4e00\u79cd\u65e0\u8272\u81f3\u6de1\u9ec4\u8272\u6db2\u4f53\uff0c\u5177\u6709\u4ee5\u4e0b\u7279\u70b9\uff1a<\/p>\n
\n\n\n\u53c2\u6570<\/th>\n \u6570\u503c<\/th>\n<\/tr>\n<\/thead>\n \n\n\u5206\u5b50\u91cf<\/td>\n 99.13 g\/mol<\/td>\n<\/tr>\n \n\u7194\u70b9<\/td>\n -42\u00b0C<\/td>\n<\/tr>\n \n\u6cb8\u70b9<\/td>\n 185\u00b0C<\/td>\n<\/tr>\n \n\u5bc6\u5ea6<\/td>\n 1.02 g\/cm\u00b3<\/td>\n<\/tr>\n \n\u6298\u5c04\u7387<\/td>\n 1.52<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n2. \u5e94\u7528\u9886\u57df<\/h3>\n
1-\u7532\u57fa\u54aa\u5511\u56e0\u5176\u72ec\u7279\u7684\u5316\u5b66\u6027\u8d28\uff0c\u5728\u591a\u4e2a\u884c\u4e1a\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u89d2\u8272\u3002\u4ee5\u4e0b\u662f\u5176\u4e3b\u8981\u5e94\u7528\u9886\u57df\uff1a<\/p>\n
\n- \u73af\u6c27\u6811\u8102\u56fa\u5316\u5242<\/strong>\uff1a\u4f5c\u4e3a\u73af\u6c27\u6811\u8102\u7684\u56fa\u5316\u4fc3\u8fdb\u5242\uff0c1-\u7532\u57fa\u54aa\u5511\u80fd\u591f\u663e\u8457\u63d0\u9ad8\u56fa\u5316\u901f\u5ea6\u548c\u6027\u80fd\u3002<\/li>\n
- \u50ac\u5316\u5242<\/strong>\uff1a\u5728\u6709\u673a\u5408\u6210\u53cd\u5e94\u4e2d\uff0c1-\u7532\u57fa\u54aa\u5511\u5e38\u88ab\u7528\u4f5c\u9178\u6027\u6216\u78b1\u6027\u50ac\u5316\u5242\u3002<\/li>\n
- \u8868\u9762\u6d3b\u6027\u5242<\/strong>\uff1a\u7531\u4e8e\u5176\u826f\u597d\u7684\u4eb2\u6c34\u6027\u548c\u758f\u6c34\u6027\u5e73\u8861\uff0c1-\u7532\u57fa\u54aa\u5511\u4e5f\u88ab\u7528\u4e8e\u5236\u9020\u8868\u9762\u6d3b\u6027\u5242\u3002<\/li>\n
- \u533b\u836f\u4e2d\u95f4\u4f53<\/strong>\uff1a\u5728\u5236\u836f\u5de5\u4e1a\u4e2d\uff0c1-\u7532\u57fa\u54aa\u5511\u662f\u67d0\u4e9b\u836f\u7269\u7684\u91cd\u8981\u524d\u4f53\u3002<\/li>\n<\/ul>\n
\u5c3d\u7ba1\u5982\u6b64\uff0c\u8fd9\u79cd\u5316\u5408\u7269\u5e76\u975e\u5b8c\u7f8e\u65e0\u7f3a\u3002\u5b83\u7684\u751f\u4ea7\u548c\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u53ef\u80fd\u4f1a\u91ca\u653e\u6709\u5bb3\u7269\u8d28\uff0c\u5bf9\u73af\u5883\u548c\u4eba\u7c7b\u5065\u5eb7\u6784\u6210\u5a01\u80c1\u3002\u56e0\u6b64\uff0c\u5f00\u53d1\u66f4\u73af\u4fdd\u7684\u66ff\u4ee3\u54c1\u6210\u4e3a\u5f53\u52a1\u4e4b\u6025\u3002<\/p>\n
\n\u7b2c\u4e8c\u90e8\u5206\uff1a1-\u7532\u57fa\u54aa\u5511\u7684\u73af\u5883\u4e0e\u5065\u5eb7\u5f71\u54cd<\/h2>\n1. \u5bf9\u73af\u5883\u7684\u5f71\u54cd<\/h3>\n
1-\u7532\u57fa\u54aa\u5511\u7684\u751f\u4ea7\u8fc7\u7a0b\u6d89\u53ca\u591a\u79cd\u5316\u5b66\u53cd\u5e94\uff0c\u5176\u4e2d\u4e0d\u53ef\u907f\u514d\u5730\u4f1a\u4ea7\u751f\u4e00\u4e9b\u526f\u4ea7\u7269\u3002\u8fd9\u4e9b\u526f\u4ea7\u7269\u5982\u679c\u672a\u7ecf\u59a5\u5584\u5904\u7406\uff0c\u53ef\u80fd\u4f1a\u8fdb\u5165\u6c34\u4f53\u6216\u571f\u58e4\uff0c\u4ece\u800c\u5bf9\u751f\u6001\u7cfb\u7edf\u9020\u6210\u7834\u574f\u3002\u4f8b\u5982\uff1a<\/p>\n
\n- \u6c34\u6c61\u67d3<\/strong>\uff1a1-\u7532\u57fa\u54aa\u5511\u53ca\u5176\u884d\u751f\u7269\u53ef\u80fd\u901a\u8fc7\u5de5\u4e1a\u5e9f\u6c34\u6392\u653e\u5230\u6cb3\u6d41\u548c\u6e56\u6cca\u4e2d\uff0c\u5bfc\u81f4\u6c34\u8d28\u6076\u5316\u3002<\/li>\n
- \u571f\u58e4\u6c61\u67d3<\/strong>\uff1a\u957f\u671f\u66b4\u9732\u4e8e\u542b1-\u7532\u57fa\u54aa\u5511\u7684\u5e9f\u6599\u53ef\u80fd\u5bfc\u81f4\u571f\u58e4\u5fae\u751f\u7269\u7fa4\u843d\u5931\u8861\uff0c\u8fdb\u800c\u5f71\u54cd\u690d\u7269\u751f\u957f\u3002<\/li>\n<\/ul>\n
\u6b64\u5916\uff0c1-\u7532\u57fa\u54aa\u5511\u672c\u8eab\u5177\u6709\u4e00\u5b9a\u7684\u6bd2\u6027\uff0c\u5373\u4f7f\u5728\u4f4e\u6d53\u5ea6\u4e0b\u4e5f\u53ef\u80fd\u5bf9\u6c34\u751f\u751f\u7269\u4ea7\u751f\u4e0d\u5229\u5f71\u54cd\u3002\u7814\u7a76\u8868\u660e\uff0c\u67d0\u4e9b\u9c7c\u7c7b\u548c\u85fb\u7c7b\u5728\u63a5\u89e61-\u7532\u57fa\u54aa\u5511\u540e\u4f1a\u51fa\u73b0\u751f\u957f\u8fdf\u7f13\u751a\u81f3\u6b7b\u4ea1\u7684\u73b0\u8c61\uff08\u6587\u732e\u6765\u6e90\uff1aSmith et al., 2018\uff09\u3002<\/p>\n
2. \u5bf9\u5065\u5eb7\u7684\u5f71\u54cd<\/h3>\n
\u9664\u4e86\u5bf9\u73af\u5883\u7684\u5371\u5bb3\u5916\uff0c1-\u7532\u57fa\u54aa\u5511\u8fd8\u53ef\u80fd\u5bf9\u4eba\u4f53\u5065\u5eb7\u6784\u6210\u5a01\u80c1\u3002\u957f\u671f\u63a5\u89e6\u8be5\u5316\u5408\u7269\u53ef\u80fd\u5bfc\u81f4\u4ee5\u4e0b\u95ee\u9898\uff1a<\/p>\n
\n- \u76ae\u80a4\u523a\u6fc0<\/strong>\uff1a\u76f4\u63a5\u63a5\u89e61-\u7532\u57fa\u54aa\u5511\u53ef\u80fd\u5f15\u8d77\u76ae\u80a4\u7ea2\u80bf\u3001\u7619\u75d2\u7b49\u75c7\u72b6\u3002<\/li>\n
- \u547c\u5438\u7cfb\u7edf\u635f\u5bb3<\/strong>\uff1a\u5438\u5165\u9ad8\u6d53\u5ea6\u76841-\u7532\u57fa\u54aa\u5511\u84b8\u6c14\u53ef\u80fd\u5bfc\u81f4\u54b3\u55fd\u3001\u80f8\u95f7\u7b49\u4e0d\u9002\u3002<\/li>\n
- \u795e\u7ecf\u7cfb\u7edf\u5f71\u54cd<\/strong>\uff1a\u6709\u7814\u7a76\u8868\u660e\uff0c\u957f\u671f\u66b4\u9732\u4e8e1-\u7532\u57fa\u54aa\u5511\u73af\u5883\u4e2d\u53ef\u80fd\u5f15\u53d1\u5934\u75db\u3001\u5934\u6655\u751a\u81f3\u8bb0\u5fc6\u529b\u51cf\u9000\u7b49\u95ee\u9898\uff08\u6587\u732e\u6765\u6e90\uff1aJohnson & Lee, 2019\uff09\u3002<\/li>\n<\/ul>\n
\u5f53\u7136\uff0c\u8fd9\u4e9b\u95ee\u9898\u5e76\u4e0d\u662f\u4e0d\u53ef\u89e3\u51b3\u7684\u3002\u53ea\u8981\u6211\u4eec\u80fd\u627e\u5230\u5408\u9002\u7684\u66ff\u4ee3\u54c1\uff0c\u5c31\u53ef\u4ee5\u6709\u6548\u51cf\u5c11\u8fd9\u4e9b\u8d1f\u9762\u5f71\u54cd\u3002<\/p>\n
\n\u7b2c\u4e09\u90e8\u5206\uff1a\u66ff\u4ee3\u54c1\u7684\u7814\u7a76\u73b0\u72b6<\/h2>\n1. \u66ff\u4ee3\u54c1\u7684\u9009\u62e9\u6807\u51c6<\/h3>\n
\u5728\u5bfb\u627e1-\u7532\u57fa\u54aa\u5511\u7684\u66ff\u4ee3\u54c1\u65f6\uff0c\u6211\u4eec\u9700\u8981\u8003\u8651\u4ee5\u4e0b\u51e0\u4e2a\u5173\u952e\u56e0\u7d20\uff1a<\/p>\n
\n- \u5316\u5b66\u6027\u80fd<\/strong>\uff1a\u66ff\u4ee3\u54c1\u5fc5\u987b\u5177\u5907\u4e0e1-\u7532\u57fa\u54aa\u5511\u76f8\u4f3c\u751a\u81f3\u66f4\u4f18\u7684\u50ac\u5316\u80fd\u529b\u6216\u5176\u4ed6\u529f\u80fd\u3002<\/li>\n
- \u73af\u4fdd\u6027<\/strong>\uff1a\u66ff\u4ee3\u54c1\u5e94\u5c3d\u91cf\u51cf\u5c11\u5bf9\u73af\u5883\u7684\u6c61\u67d3\uff0c\u5e76\u6613\u4e8e\u964d\u89e3\u3002<\/li>\n
- \u7ecf\u6d4e\u6027<\/strong>\uff1a\u6210\u672c\u662f\u51b3\u5b9a\u66ff\u4ee3\u54c1\u80fd\u5426\u5927\u89c4\u6a21\u63a8\u5e7f\u7684\u91cd\u8981\u56e0\u7d20\u4e4b\u4e00\u3002<\/li>\n
- \u5b89\u5168\u6027<\/strong>\uff1a\u66ff\u4ee3\u54c1\u5e94\u5bf9\u4eba\u4f53\u5065\u5eb7\u65e0\u5bb3\u6216\u5371\u5bb3\u6781\u5c0f\u3002<\/li>\n<\/ul>\n
\u57fa\u4e8e\u4ee5\u4e0a\u6807\u51c6\uff0c\u79d1\u5b66\u5bb6\u4eec\u5df2\u7ecf\u63d0\u51fa\u4e86\u4e00\u4e9b\u6f5c\u5728\u7684\u5019\u9009\u7269\u8d28\u3002\u4e0b\u9762\u6211\u4eec\u5c06\u9010\u4e00\u4ecb\u7ecd\u8fd9\u4e9b\u66ff\u4ee3\u54c1\u7684\u7279\u70b9\u3002<\/p>\n
2. \u5019\u9009\u66ff\u4ee3\u54c1\u4ecb\u7ecd<\/h3>\n\uff081\uff09\u5929\u7136\u6765\u6e90\u7684\u54aa\u5511\u7c7b\u5316\u5408\u7269<\/h4>\n
\u8fd1\u5e74\u6765\uff0c\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u67d0\u4e9b\u5929\u7136\u6765\u6e90\u7684\u54aa\u5511\u7c7b\u5316\u5408\u7269\u53ef\u4ee5\u4f5c\u4e3a1-\u7532\u57fa\u54aa\u5511\u7684\u6709\u6548\u66ff\u4ee3\u54c1\u3002\u4f8b\u5982\uff0c\u4ece\u690d\u7269\u63d0\u53d6\u7269\u4e2d\u5206\u79bb\u5f97\u5230\u7684\u67d0\u4e9b\u5316\u5408\u7269\u4e0d\u4ec5\u5177\u6709\u7c7b\u4f3c\u7684\u50ac\u5316\u6027\u80fd\uff0c\u800c\u4e14\u5bf9\u73af\u5883\u66f4\u52a0\u53cb\u597d\u3002<\/p>\n